TABLE 2.
Functional enrichment analysis of upregulated genes in the old mouse ovary compared to young mouse.
| Category | Term | Description | Count | % | p value |
| BP | GO:0007159 | Leukocyte cell–cell adhesion | 53 | 6.4% | 5.35E–21 |
| BP | GO:0022407 | Regulation of cell–cell adhesion | 58 | 7.0% | 3.23E–20 |
| BP | GO:0042110 | T cell activation | 64 | 7.7% | 2.21E–19 |
| BP | GO:1903037 | Regulation of leukocyte cell–cell adhesion | 47 | 5.7% | 1.71E–18 |
| BP | GO:0046651 | Lymphocyte proliferation | 48 | 5.8% | 5.15E–18 |
| CC | GO:0005930 | Axoneme | 31 | 3.7% | 7.76E–18 |
| CC | GO:0097014 | Ciliary plasm | 31 | 3.7% | 9.92E–18 |
| CC | GO:0032838 | Plasma membrane bounded cell projection cytoplasm | 31 | 3.7% | 3.48E–14 |
| CC | GO:0044441 | Ciliary part | 50 | 6.0% | 1.27E–12 |
| CC | GO:0044447 | Axoneme part | 15 | 1.8% | 1.83E–12 |
| MF | GO:0003774 | Motor activity | 21 | 2.6% | 8.49E–09 |
| MF | GO:0004896 | Cytokine receptor activity | 16 | 2.0% | 3.34E–07 |
| MF | GO:0045503 | Dynein light-chain binding | 9 | 1.1% | 4.88E–07 |
| MF | GO:1990939 | ATP-dependent microtubule motor activity | 11 | 1.4% | 6.23E–07 |
| MF | GO:0042608 | T cell receptor binding | 7 | 0.9% | 6.35E–07 |
| KEGG | mmu04514 | Cell adhesion molecules (CAMs) | 41 | 11.5% | 7.49E–21 |
| KEGG | mmu04145 | Phagosome | 30 | 8.4% | 3.83E–11 |
| KEGG | mmu04640 | Hematopoietic cell lineage | 21 | 5.9% | 1.65E–10 |
| KEGG | mmu05416 | Viral myocarditis | 20 | 5.6% | 2.68E–10 |
| KEGG | mmu05330 | Allograft rejection | 17 | 4.8% | 3.39E–10 |