TABLE 3.

Functional enrichment analysis of downregulated genes in the old mouse ovary compared to young mouse.

Category	Term	Description	Count	%	p value
BP	GO:0008585	Female gonad development	7	14.0%	4.56E–09
BP	GO:0009566	Fertilization	8	16.0%	5.48E–09
BP	GO:0046545	Development of primary female sexual characteristics	7	14.0%	5.48E–09
BP	GO:0001541	Ovarian follicle development	6	12.0%	8.00E–09
BP	GO:2000194	Regulation of female gonad development	4	8.0%	2.57E–08
CC	GO:0042627	Chylomicron	2	4.0%	0.00028
CC	GO:0034361	Very-low-density lipoprotein particle	2	4.0%	0.000643
CC	GO:0034385	Triglyceride-rich plasma lipoprotein particle	2	4.0%	0.000643
CC	GO:0034364	High-density lipoprotein particle	2	4.0%	0.001151
CC	GO:0034358	Plasma lipoprotein particle	2	4.0%	0.002444
MF	GO:0005160	Transforming growth factor beta receptor binding	2	4.0%	0.000205
MF	GO:0017127	Cholesterol transporter activity	2	4.0%	0.000844
KEGG	mmu04977	Vitamin digestion and absorption	2	14.3%	0.000657
KEGG	mmu04975	Fat digestion and absorption	2	14.3%	0.001829
KEGG	mmu04979	Cholesterol metabolism	2	14.3%	0.002735