FIGURE 1.

circ_SEPT9 is up‐regulated in oral squamous cell carcinoma. A, Special primers were designed to detect the linear and circular SEPT9 in gDNA and cDNA by reverse transcript PCR. B, OligodT and random primers were used in quantitative real‐time PCR (qRT‐PCR) in SCC‐15 cell line. circ_SEPT9 was absent in poly(A) enriched RNAs. C, qRT‐PCR was performed with RNase R treatment. Circular RNA was resistant to RNase R treatment. D, qRT‐PCR analysis was performed to detect the expression of circ_SEPT9 in OSCC and normal cell line HOK. E, qRT‐PCR analysis was performed to detect the expression of circ_SEPT9 in OSCC tissue and the adjacent normal tissue