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. 2020 Oct 17;24(22):13278–13288. doi: 10.1111/jcmm.15944

Figure 5.

Figure 5

fIHC staining for CD68+ macrophages in the pFUS‐targeted myocardium (n = 3/group). A and B, Long axis LV section of fIHC in SHAM and post‐pFUS shows the significantly higher number of Macrophage (CD68+ cells) was observed at post‐12 h compared with the SHAM. White box represents the region of interest in the heart. C‐G, Time course of macrophage infiltration revealed that pFUS treatment resulted in significant number of macrophages in pFUS‐targeted region at post‐12 h. (H) There was a quantitative increase in fluorescence detected at 12 h post‐pFUS for macrophages. C‐G represents Sham (p0), post‐3 (p3), post‐12 (p12), post‐24 (p24) and post‐48 (p48) hours at post‐pFUS, respectively. Red colour represents the macrophage (CD68+ cells). Asterisks represent the statistical significance set at P < .05 based on ANOVA. Scale bar = 2 mm (A) and 100 µm (D‐M)