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Transcriptional regulation of cardiovascular lncRNAs via interactions with multiple chromatin‐modifying complexes. The mode of action of cardiac lncRNAs, such as Fendrr, is shown in the guiding scaffold model (A, C); In the trapped scaffold model, Bvht and Chaer detach histone‐modifying enzymes, such as PRC2, from target genome sites (B). lncRNA, long non‐coding RNA; PRC, polycomb repressive complex; TrxG/MLL, trithorax/mixed lineage leukaemia
