Table 1.

Haemodynamic and echocardiographic parameters

	Sham	AMI 1D	AMI 7D	AMI 14D	AMI 14D + non‐HBO‐exosome	AMI 14D + HBO‐exosome	AMI 14D + MALAT1 LNA GapmeR + HBO‐exosome	AMI 14D + scrambleLNA GapmeR + HBO‐exosome	AMI 14D + AntagomiR miR‐92a
N	5	5	5	5	5	5	5	5	5
Body weight, g	321 ± 26	322 ± 31	302 ± 36	276 ± 38	268 ± 43	304 ± 34	282 ± 49	297 ± 32	310 ± 33
Heart weight, mg	802 ± 21	821 ± 35	855 ± 47	859 ± 46	859 ± 46	831 ± 41	865 ± 52	829 ± 44	811 ± 49
Heart weight/body weight, mg/g	2.4 ± 0.6	2.5 ± 0.4	2.9 ± 0.9	3.1 ± 0.5	3.1 ± 0.8	2.6 ± 0.8	3.0 ± 0.7	2.6 ± 0.7	2.7 ± 0.4
Heart rate, min	317 ± 21	437 ± 55 +	404 ± 48 +	385 ± 49 +	385 ± 49	341 ± 33	392 ± 26	350 ± 40	349 ± 28
MAP, mm Hg	115 ± 12	79 ± 9 +	91 ± 6 +	95 ± 5 +	93 ± 9	103 ± 6	92 ± 3	105 ± 7	102 ± 7
LVEDD, mm	6.3 ± 0.4	6.9 ± 0.6	7.0 ± 0.4	7.4 ± 0.3 +	7.3 ± 0.5	6.5 ± 0.3*	7.5 ± 0.65	6.7 ± 0.84*	6.4 ± 0.95*
LVESD, mm	2.7 ± 0.5	4.2 ± 0.3	4.4 ± 0.5	4.7 ± 0.4 +	4.7 ± 0.5	3.3 ± 0.7*	4.7 ± 0.6	3.3 ± 0.4*	3.3 ± 0.4*
FS, %	57 ± 5	40 ± 6	36 ± 4 +	36 ± 4 +	35 ± 7	49 ± 7*	37 ± 6	50 ± 5*	49 ± 76*

Abbreviations: FS, fraction shortening; LVEDD, left ventricular end‐diastolic dimension; LVESD, left ventricular end‐systolic dimension; MAP, mean arterial pressure.

⁺ P < .05 vs sham.

^* P < .05 vs AMI 14D.