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. 2020 Nov 25;12:12151–12162. doi: 10.2147/CMAR.S258532

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© 2020 Zhang et al.

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Overexpression of LINC01089 inhibited proliferation, migration, and invasion. (A) LINC01089 was overexpressed following transfection with LINC01089-pcDNA3.1. LINC01089 expression was measured by quantitative reverse transcription-polymerase chain reaction in A549 and SK-MES-1 following transfection with pcDNA3.1 (ov-NC) and LINC01089-pcDNA3.1 (ov- LINC01089) at 48 h. *P < 0.05. (B) Proliferation of A549 and SK-MES-1 was measured using MTS assay 48 h post-transfection. *P < 0.05. (C and D) Migration and invasion of A549 and SK-MES-1 were measured using transwell assay 48 h post-transfection. *P < 0.05.

Abbreviations: ov, overexpression; NC, negative control.