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. 2020 Nov 13;23(12):101798. doi: 10.1016/j.isci.2020.101798

Figure 3.

Figure 3

Bacterially Derived Tryptamine Attenuates Colitis Severity as Measured by Disease Activity Index and Epithelial Permeability in Female Mice Following DSS Administration

(A–C) Graphs show change in the DAI over a 7-day period post-DSS administration in both male and female Trp D+ and Trp D monocolonized mice. n = 12–14 (7–8 males; 5–6 females).

(D–F) Graphs highlight change in 4-kDa FITC flux across proximal colon tissue over two hours in both male and female DSS-treated Trp D+ and Trp D monocolonized mice. n = 9 (4–5 males; 4–5 females). Data are mean ± SEM. ∗p < 0.05; two-way ANOVA with Bonferroni post hoc.