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T50 values determined via thioflavin-T fluorescence assays for wild type human amylin and the three consensus sequences. Experiments were conducted at 25°C in PBS pH 7.4 at 16 μM peptide concentration. Reported uncertainties are the apparent standard deviation from 12 measurements.
| Peptide | T50 (hrs) |
|---|---|
| Human amylin | 3.3 ± 1.0 |
| Primate consensus | 10.1 ± 2.6 |
| Mammalian consensus | 80.1 ± 28.7 |
| Vertebrate consensus | 20.8 ± 6.8 |
