. 2020 Sep 24;252(3):e5517. doi: 10.1002/path.5517

Table 2.

Correlation of ADAM10 expression on renal biopsy specimens with major clinicopathological parameters in patients with the pathological diagnosis of IgA nephropathy (IgAN).

Clinicopathological parameters	n	ADAM10 expression		χ² value	P value
Clinicopathological parameters	n	Low	High	χ² value	P value
Age (years)
< 41	39	19	20	0.013	0.908
≥ 41	42	21	21	0.013	0.908
Gender
Male	42	22	20	0.314	0.575
Female	39	18	21	0.314	0.575
Baseline systolic blood pressure (mmHg)
< 133	40	21	19	0.307	0.579
≥ 133	41	19	22	0.307	0.579
Baseline diastolic blood pressure (mmHg)
< 82	37	19	18	0.595	0.441
≥ 82	44	21	23	0.595	0.441
Baseline GLU (mm)
< 4.41	40	21	19	0.307	0.579
≥ 4.41	41	19	22	0.307	0.579
Baseline TC (mm)
< 4.23	38	17	21	0.618	0.432
≥ 4.23	43	23	20	0.618	0.432
Baseline TG (mm)
< 1.47	40	23	17	2.083	0.149
≥ 1.47	41	17	24	2.083	0.149
Baseline Scr (μm)
< 104	40	26	14	7.711	0.005
≥ 104	41	14	27	7.711	0.005
Baseline BUN (mm)
< 6.65	40	26	14	7.711	0.005
≥ 6.65	41	14	27	7.711	0.005
Baseline cystatin C (mg/l)
< 1.39	41	25	16	4.464	0.035
≥ 1.39	40	15	25	4.464	0.035
Baseline eGFR (EPI‐Cr) (ml/min)
< 68.61	40	13	27	9.011	0.003
≥ 68.61	41	27	14	9.011	0.003
Baseline urinary protein (g/l)
< 0.87	40	23	17	2.083	0.149
≥ 0.87	41	17	24	2.083	0.149
Fibrosis (%)
< 25	40	31	9	24.994	< 0.001
≥ 25	41	9	32	24.994	< 0.001

p < 0.05 was considered to have statistical significance. Values in bold are statistically significant. GLU, glucose; TC, total cholesterol; TG, triglyceride; Scr, serum creatinine; BUN, blood urea nitrogen; eGFR, estimated glomerular filtration rate.