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. Author manuscript; available in PMC: 2021 Jun 1.
Published in final edited form as: Prim Care. 2020 Feb 27;47(2):331–349. doi: 10.1016/j.pop.2020.02.010

Table 6.

2015 Centers for Disease Control and Prevention guidelines for sexually transmitted infection prophylaxis after sexual assault

Gonorrhea Ceftriaxone 250 mg IM (single dose)

Chlamydia Azithromycin 1 g PO (single dose)

Trichomonas Metronidazole 2 g PO or tinidazole 2 g PO (single doses)

Pregnancy Levonorgestrel 1.5 mg PO or ulipristal acetate 30 mg PO or Cu IUD

Consider as indicated:
 HIV PEP ≤72 h exposure
 HPV vaccine, if ≥9 y and not fully immunized
 Tdap (tetanus, diphtheria, acellular pertussis) booster
 Hepatitis B vaccine and hepatitis B immune globulin (HBIG)
 Antiemetic avoiding ondansetron if susceptibility to prolongation of the QT interval exists

Adapted from Division of STD Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention. Sexual assault and abuse and STDs. In: 2015 sexually transmitted diseases: treatment guidelines 2015. Available at: https://www.cdc.gov/std/tg2015/default.htm