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. Author manuscript; available in PMC: 2021 Jun 1.
Published in final edited form as: Prim Care. 2020 Feb 27;47(2):331–349. doi: 10.1016/j.pop.2020.02.010

Table 7.

Follow-up

SAFE or Initial Examination 3–7 da 2 wka 3–6 wka 3 moa 6 moa
UDS if suspect drug facilitation ≤96 h
Pregnancy X ≥7 d
Anogenital examination X Reevaluate any positive findings Evaluate for warts; primary syphilis with dark field examination if signs present
Wet mount if discharge present X X
Gonorrhea, chlamydia, trichomonas if negative initial test and no empiric treatment X ≥7 d or, not initially tested if signs present b
Medication tolerance/adherence. Adjust medications accordingly X X
ALT, AST, creatinine, complete blood count if taking PEP X X
HIV combined antigen/antibody, with confirmatory test as needed X X (4 wk if fourth generation; 6 wk if third generation) X In addition, only if third generation
Hepatitis B surface antibody X
Hepatitis Cc X x
Nontreponemal syphilis (RPR or VDRL), with confirmatory test as needed X X X X
Psychiatric well-being X X X X X X
a

Time from last suspected encounter.

b

Retest sexually active women 2 wk to 3 mo after trichomonas treatment. Retest chlamydia and gonorrhea 3 mo after treatment in both genders for assessment of new infection if sexually active.

c

Hepatitis C serology may be considered, but is not substantiated by research in the circumstance of sexual assault.