TABLE 1.

Characteristics of the six microarray datasets in our integrated analysis

GSE ID	Control	Acute stage (0‐3d)	Latent stage (4‐14d)	Chronic stage (14d later)	Tissue	Platform	Year
GSE73878	IL a ‐sham‐7d: 4 IL‐sham‐28d: 5	N/A	IL‐KA b ‐7d: 8	IL‐KA‐28d: 9 IL‐KA‐60d:14	M e ‐H	GPL6885	2015
GSE49849	Sham‐7d: 5sham‐30d: 5	N/A	stimu c ‐7d: 5	stimu‐30d: 5	R h ‐DG	GPL11534	2013
GSE88992	Saline‐6h: 3 Saline‐12h: 3 Saline‐24h: 3	KA‐6h: 3 KA‐12h: 3 KA‐24h: 2	N/A	N/A	M‐H g	GPL1261	2016
GSE14763	Control: 3	Pilo d ‐3d: 5	Pilo‐7d: 5	Pilo‐chronic: 5	R‐H	GPL2896	2009
GSE47752	Pilo control: 17 KA control: 12	Pilo‐1d: 12 KA‐1d: 12 Pilo‐3d: 12 KA‐3d: 13	Pilo‐10d: 12 KA‐10d: 12	N/A	R‐DG f	GPL1355	2013
GSE49030	Control‐1h: 9	KA‐1h: 3 KA‐4h: 6 KA‐8h: 3 KA‐24h: 3	N/A	N/A	M‐H	GPL1261	2013

A total of six microarrays were included in the integrated analysis. In these microarrays, seizure was induced in rat or mouse by either pilocarpine or kainic acid or electrical stimulation. Hippocampus or dentate gyrus of the epileptic rats or mice was sampled at different time points for expression profile detection in microarray platform. The samples in six included microarrays were divided according to sampling time after model establishment into three groups: acute stage (0‐3d), latent stage (4d‐14d), and chronic stage (the first spontaneous recurrent seizure or after 14d).

^aipsilateral;

^bkainic acid;

^celectrical stimulation of amygdala;

^dpilocarpine;

^emouse;

^fdentate gyrus;

^ghippocampus;

^hrat.