Table 1. Biochemical inhibition of MerTK kinase domain and biophysical binding by surface plasmon resonance (SPR).

	Biochem	SPR — dephosphorylated MerTK		SPR — phosphorylated MerTK
Compound	pIC501.	pKD2	t1/2 (min)	pKD3	t1/2 (min)

Unless stated otherwise, all data reported are a mean of at least three independent measurements.

¹pIC₅₀ SEM < 0.30.

²pK_d SEM < 0.21.

³pK_d SEM < 0.20.

*SPR data could not be reliably determined for UNC2025/MRX-6313.