Table 2.

Five-fold cross validation statistical significance (p-value) using different scores. A. Rank normalized score (pairwise; Wilcoxon matched-pairs signed rank test), B. Rank normalized score (Unpaired Comparison; Mann-Whitney U test), C. ΔRNS (Unpaired Comparison; Mann-Whitney U test). Assay Central (AC); AdaBoost (ada); Bernoulli Naïve-Bayes (bnb); k-nearest neighbors (knn); Random Forest (rf); support vector classification (svc); Deep Neural Networks (DL).

A.
	ada	bnb	DL	knn	rf	svc	AC
ada	N/A	0.0078**	0.1094	0.0078**	0.0078**	0.0078**	0.0156*
bnb	0.0078**	N/A	0.0391*	0.0078**	0.0078**	0.0078**	0.0078**
DL	0.1094	0.0391*	N/A	0.5469	0.6406	0.1953	0.6406
knn	0.0078**	0.0078**	0.5469	N/A	0.0781	0.5469	0.1953
rf	0.0078**	0.0078**	0.6406	0.0781	N/A	0.1953	0.9453
svc	0.0078**	0.0078**	0.1953	0.5469	0.1953	N/A	0.3125
AC	0.0156*	0.0078**	0.6406	0.1953	0.9453	0.3125	N/A
B.
	ada	bnb	DL	knn	rf	svc	AC
ada	N/A	0.1949	0.3281	0.1049	0.1605	0.1049	0.1605
bnb	0.1949	N/A	0.1304	0.0499*	0.1304	0.0281*	0.0830
DL	0.3281	0.1304	N/A	0.9591	0.7984	0.6454	0.7984
knn	0.1049	0.0499*	0.9591	N/A	0.3823	0.7984	0.5737
rf	0.1605	0.1304	0.7984	0.3823	N/A	0.4418	0.9591
svc	0.1049	0.0281*	0.6454	0.7984	0.4418	N/A	0.5737
AC	0.1605	0.0830	0.7984	0.5737	0.9591	0.5737	N/A
C.
	ada	bnb	DL	knn	rf	svc	AC
ada	N/A	0.1949	0.0207*	0.0011**	0.0281*	0.0095**	0.0626
bnb	0.1949	N/A	0.0047**	0.0002***	0.0002***	0.0065**	0.0068**
DL	0.0207*	0.0047**	N/A	0.5526	0.4418	0.1183	0.8527
knn	0.0011**	0.0002***	0.5526	N/A	0.0626	0.3579	0.1790
rf	0.0281*	0.0002***	0.4418	0.0626	N/A	0.0443*	0.8527
svc	0.0095**	0.0065**	0.1183	0.3579	0.0443*	N/A	0.2171
AC	0.0626	0.0068**	0.8527	0.1790	0.8527	0.2171	N/A