Table 4.
Selection of relevant Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) terms of the differentially expressed genes in glia in the contralateral hippocampus (CLH) at 24 h after kainate-induced status epilepticus.
|
Upregulated in glia (74 genes) |
Downregulated in glia (22 genes) |
|
|---|---|---|
| GO | Regulation of angiogenesis | G protein-coupled nucleotide receptor activity |
| Regulation of cell motility | Purinergic receptor activity | |
| Positive regulation of cell migration | Oxidation-reduction process | |
| Positive regulation of cell death | – | |
| Angiogenesis | – | |
| Regulation of interleukin-1 beta production | – | |
| Tumor necrosis factor production | – | |
| Neurogenesis | – | |
| KEGG | TNF signaling pathway | – |
| IL-17 signaling pathway | – | |
| ECM-receptor interaction | – | |
| MAPK signaling pathway | – | |
| Cytokine-cytokine receptor interaction | – | |
| Growth hormone synthesis, secretion and action | – | |
| JAK-STAT signaling pathway | – | |
| VEGF signaling pathway | – | |
| p53 signaling pathway | – | |
| PI3K-Akt signaling pathway | – | |
| NF-kappa B signaling pathway | – |
Relevant GO and KEGG terms amongst significantly differentially expressed genes (FDR < 0.25).