Table 3.
Target Gene List (n=33) for the Intersection of Five miRNAs Using DIANA mirPath v3.0 for the cfs0>CFS Condition (“The DIANA list”) Organized by Function
| Gene symbol | Protein name | Chromosome location |
|---|---|---|
| Adherens junction hsa04520 | ||
| ACTB | actin beta | 7p22.1 |
| CDC42 | cell division cycle 42 | 1p36.12 |
| DYNC1H1 | dynein cytoplasmic 1 heavy chain 1 | 14q32.31 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 6q21 |
| IGF1R | insulin like growth factor 1 receptor | 15q26.3 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 15q26.1 |
| PTPRJ | protein tyrosine phosphatase, receptor type J | 11p11.2 |
| TGFBR1 | transforming growth factor beta receptor 1 | 9q22.33 |
| RNA binding GO:0003723 | ||
| DCP2 | decapping mRNA 2 | 5q22.2 |
| EWSR1 | EWS RNA binding protein 1 | 22q12.2 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 14q11.2 |
| NCL | nucleolin | 2q37.1 |
| NUFIP2 | nuclear FMR1 interacting protein 2 | 17q11.2 |
| PCBP2 | poly(rC) binding protein 2 | 12q13.13 |
| PRPF8 | pre-mRNA processing factor 8 | 17p13.3 |
| Transcription, DNA templated GO:0006351 | ||
| ELK4 | ETS transcription factor | 1q32.1 |
| KMT2D | lysine methyl transferase 2D | 12q13.12 |
| SETD7 | SET domain containing lysine methyl transferase 7 | 4q31.1 |
| SIN3A | SIN3 transcription regulator family member A | 15q24.2 |
| TCF3 | transcription factor 3 | 19p13.3 |
| ZNF703 | zinc finger protein 703 | 8p11.23 |
| Nucleoplasm GO:0005654 | ||
| ASH1L | ASH1 like histone lysine methyltransferase | 1q22 |
| BAG6 | BCL2 associated athanogene 6 | 6p21.33 |
| CCND2 | cyclin D2 | 12p13.32 |
| CCNE2 | cyclin E2 | 8q22.1 |
| DYRK1A | dual specificity tyrosine phosphorylation regulated kinase 1A | 21q22.13 |
| H3F3B | H3 histone family member 3B | 17q25.1 |
| MCM7 | minichromosome maintenance complex component 7 | 7q22.1 |
| SUV420H1 | lysine methyl transferase 5B | 11q13.2 |
| Other | ||
| FASN | fatty acid synthase | 17q25.3 |
| SCARB2 | scavenger receptor class B member 2 | 4q21.1 |
| SCD | stearoyl-CoA desaturase | 10q24.31 |
| SPOPL | speckle type BTB/POZ protein like | 2q22.1 |