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. 2020 Nov 30;41(3):585–593. doi: 10.1007/s00296-020-04746-7

Table 2.

Rheumatologists’ current approaches to and attitudes about inadequate response to TNFi therapies

% n
Percentage of patients believed by rheumatologist to respond adequately to an initial TNFi therapy
 Less than 20% 0.8 2
 21–39% 19.8 49
 40–59% 51.2 127
 60% or more 28.2 70
The percent of rheumatologists who are concerned or very concerned about five issues related to inadequate response to TNFi therapies
 Non-response increasing time to low disease activity state 73.0 181
 Patients paying for drugs not getting them to targets 71.0 176
 Difficulty predicting which patients will be non-responders 67.7 168
 Difficulty getting other drugs approved by payers/plans 65.7 163
 Non-responders having reduced patient satisfaction 64.1 159
Interest in a test to predict inadequate response to TNFi therapies
 Not at all interested 1.2 3
 Slightly interested 2.0 5
 Moderately interested 11.3 28
 Very interested 41.5 103
 Extremely interested 44.0 109