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. 2020 Nov 30;2(2):137–148.e4. doi: 10.1016/j.medj.2020.11.001

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Genetic Association of Blood Pressure with Incident Respiratory Disease

Association of SBP PRS and DBP PRS with incident respiratory diseases (defined in Table S2), adjusted for age, age², sex, smoking status, and the first ten principal components of population stratification in the UK Biobank. Effects are interpreted as HR per 5 mm Hg increase from the respective PRS. HR and 95% CI are displayed. SBP, systolic blood pressure; DBP, diastolic blood pressure; PRS, polygenic risk score; HR, hazard ratio.