Figure 4.

Epidemiological and Genetic Associations of Elevated Blood Pressure with Pulmonary Function Tests

(A) Association of prevalent hypertension with pulmonary function tests (PFTs), adjusted for age, age², sex, standing height, smoking status, prevalent coronary artery disease, prevalent diabetes, body mass index, and the first ten principal components of population stratification in the UK Biobank. Beta and 95% CI are displayed.

(B) Association of SBP PRS and DBP PRS PFTs, adjusted for age, age², sex, standing height, body mass index, smoking status, and the first ten principal components of population stratification in the UK Biobank. Beta values are interpreted as SD change in PFT per 5 mm Hg increase from the respective PRS. Beta and 95% CI are displayed.

FEV₁, forced expiratory volume in 1 s; FVC, forced vital capacity; HTN, hypertension.