Table 1.

COVID-19 treatment protocol proposed by the Italian Society of Infectious and Tropical Diseases.

Treatment Protocols
Patient with mild symptoms but over 70 years or/and with different diseases or/and worsening conditions	Lopinavir/Ritonavir + Chloroquine or Hydroxychloroquine	➢ Lopinavir/Ritonavir: 200/50 mg twice daily➢ Chloroquine or Hydroxychloroquine: 500 mg or 200 mg twice daily
	Darunavir /Ritonavir + Chloroquine or Hydroxychloroquine* or Darunavir/Cobicistat + Chloroquine or Hydroxychloroquine **	➢ Darunavir: 800 mg per day➢ Ritonavir: 100 mg per dayor➢ Darunavir: 800 mg per day➢ Cobicistat: 150 mg per day➢ Chloroquine: 500 mg twice per day for 20 days➢ Hydroxychloroquine: 200 mg twice a day
Patient with severe symptoms	Remdesevir + Chloroquine or Hydroxychloroquine	➢ Remdesevir: 200 mg for the first day, 100 mg daily for the following days➢ Chloroquine: 500 mg twice daily or Hydroxychloroquine: 200 mg twice per day

^*If lopinavir is not available;

^**If Lopinavir/Ritonavir is not available