Table 5.
Inhibitory Activity against Cell-to-Cell HIV Transmission by the gp120 Entry Antagonists
| IC50a (μM) | ||
|---|---|---|
| compound | TZMb-l/H9-HIV-1IIIB | TZMb-l/Molt-HIV-1ADA | 
| Ref2 | 0.46 ± 0.2 | 0.89 ± 0.14 | 
| 33 | 0.45 ± 0.1 | 1.2 ± 0.4 | 
| 8 | 0.47 ± 0.1 | 0.92 ± 0.13 | 
| BMS-626529 | 0.02 ± 0.005 | ~0.2 | 
The reported IC50 values represent the means ± standard deviation (SD), n = 3.