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. 2020 Nov 9;117(47):29851–29861. doi: 10.1073/pnas.2011301117

Fig. 6.

Fig. 6.

Overall view of the maturation factors on the intersubunit side. On the intersubunit side of the immature LSU, 11 maturation factors act together to remodel and modify the rRNA (D). (A) mt-LAF4 and mt-LAF2 occupy the position of the CP. Mt-LAF2 and mt-LAF3 interact with remodeled rRNA. (B) Mt-Rsfs together with L0R8F8 and mt-SAF32 interact with uL14m and H95 to block the SSU association. (C) Arrangement of the GTPase triptych. The GTPases mt-EngA and mt-EngB bind the rRNA H75 and H37, respectively, while mt-RbgA occupies a central place in the complex and creates a bridge between the GTPases and mt-LAF3 and mt-Rsfs.