Table 2.
Comorbidities and number of comorbidities in elderly and nonelderly patients with IPF.
| Age group <75 years n = 659 | Age group ≥75 years n = 350 | p-value | |
|---|---|---|---|
| Left heart disease, n (%) | 31 (4.7) | 36 (10.3) | 0.001 |
| Coronary artery disease, n (%) | 148 (22.5) | 129 (36.9) | <0.001 |
| Cerebrovascular diseasea, n (%) | 45 (6.8) | 28 (8.0) | 0.494 |
| Peripheral arterial diseaseb, n (%) | 17 (2.6) | 19 (5.4) | 0.020 |
| Atrial fibrillation, n (%) | 37 (5.6) | 54 (15.4) | <0.001 |
| Deep venous thrombosis, n (%) | 13 (2.0) | 10 (2.9) | 0.370 |
| Pulmonary arterial embolism, n (%) | 10 (1.5) | 11 (3.1) | 0.082 |
| Pulmonary hypertension, n (%) | 96 (14.6) | 59 (16.9) | 0.337 |
| Arterial hypertension, n (%) | 332 (50.4) | 222 (63.4) | <0.001 |
| Diabetes mellitus, n (%) | 140 (21.2) | 92 (26.3) | 0.070 |
| Emphysema, n (%) | 65 (9.9) | 36 (10.3) | 0.832 |
| Lung cancer, n (%) | 11 (1.7) | 5 (1.4) | 0.771 |
| Obstructive sleep apnoea, n (%) | 73 (11.1) | 29 (8.3) | 0.161 |
| Depression/depressive disorder, n (%) | 48 (7.3) | 9 (2.6) | 0.002 |
| Anxiety, n (%) | 32 (4.9) | 6 (1.7) | 0.013 |
| Other comorbid diseases, n (%) | 338 (51.3) | 189 (54.0) | 0.412 |
| Number of comorbidities, mean (sd) | 2.8 (2.3) | 3.6 (2.5) | <0.001 |
| None, n (%) | 89 (13.5) | 29 (8.3) | 0.001 |
| 1–3, n (%) | 354 (53.7) | 165 (47.1) | |
| ≥4, n (%) | 216 (32.8) | 156 (44.6) |
Data are presented as mean ± SD, or n (%).
a
Carotid stenosis, stroke.
b
Symptomatic or ankle brachial index <0.8.