Table 6.

Reasons for death in elderly and nonelderly patients with IPF.

	Age group <75 years n = 659	Age group ≥75 years n = 350	HR	95%CI	p-value
All cause mortality	250 (37.9%)	172 (49.1%)	1,65	1.36–2.00	<0.001
Death related to IPF	105 (15.9%)	57 (16.3%)	1,28	0.93–1.77	0,131
Death by respiratory failure	54 (8.2%)	25 (7.1%)	1,06	0.66–1.71	0,809
Death by acute exacerbation	20 (3.0%)	7 (2.0%)	0,77	0.32–1.86	0,566
Death by right heart failure	4 (0.6%)	1 (0.3%)	0,70	0.07–6.71	0,754
Death by respiratory infection/pneumonia	18 (2.7%)	14 (4.0%)	1,81	0.89–3.70	0,102
Death related to IPF but unknown reason	29 (4.4%)	17 (4.9%)	1,44	0.79–2.63	0,230
Death by complicating comorbidity	22 (3.3%)	9 (2.6%)	0,96	0.44–2.09	0,921
Death by other cause not related to IPF	24 (3.6%)	15 (4.3%)	1,51	0.80–2.86	0,201
Reasons for death unknown	99 (15.0%)	91 (26.0%)	2,23	1.68–2.96	<0.001
Lung transplantation	42 (6,4%)	0 (0.0%)
Combined endpoint (all cause mortality/lung transplantation)	283 (42.9%)	172 (49.1%)	1,47	1.22–1.78	<0.001

IPF, idiopathic pulmonary fibrosis.