Table 2.
Study | Study Population | Total Number of Samples in the Study | Type of Study | Overall Sensitivity | Overall Specificity | PPV | NPV | Positive Likelihood Ratio (LR+) | Negative Likelihood Ratio (LR−) |
---|---|---|---|---|---|---|---|---|---|
Leber et al.25 | Pediatrics and Adults | 1560 | Prospective | 94.2% | 97.7% | 74.8% | 99.6% | 41.6 | 0.06 |
Arora et al.40 | Pediatrics | 62 | Prospective | 100.0% | 93.4% | 55.6% | 100.0% | 15.3 | 0 |
Lee et al.30 | Pediatrics and Adults | 42 | Prospective | 60.0% | 100% | 100.0% | 86.7% | N/A | 0.40 |
Radmard et al.24 | Pediatrics and Adults | 705 | Retrospective | 85.7% | 98.3% | 36.8% | 99.9% | 52.2 | 0.13 |
Hanson et al.53 | Pediatrics and Adults | 342 | Retrospective | 91.8% | 88.3% | 88.4% | 91.7% | 7.8 | 0.09 |
Messacar et al.35 | Pediatrics | 138 | Retrospective | 91.1% | 97.9% | 95.3% | 95.9% | 43.3 | 0.09 |
Graf et al.36 | Pediatrics | 133 | Retrospective | 92.5% | 100.0% | 100.0% | 93.0% | N/A | 0.07 |
Piccirilli et al.41 | Pediatrics and Adults | 63 | Retrospective | 85.7% | 100.0% | 100.0% | 77.8% | N/A | 0.14 |