Fig. 1.

Gene pairs driving doublet prediction in cxds. For four datasets (panels) the first row shows all cells in (left), the annotated doublets (center) and cxds-predicted doublets (right). The following two rows depict the two gene pairs that contribute most to the cxds classifier (Section 2). For each pair (i.e. for each row), the left plot depicts the expression of one gene (presence/absence), the middle plot the expression of the other gene, while the right plot the average expression in cells that co-express both genes. We see that each gene in a pair is expressed in distinct groups of cells, and that their co-expression highlights annotated and predicted doublets