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. Author manuscript; available in PMC: 2020 Nov 30.
Published in final edited form as: Biochem Biophys Res Commun. 2020 Feb 5;524(3):730–735. doi: 10.1016/j.bbrc.2020.01.152

Fig. 4. Crotonic acid increases tumor cell proliferation partially via suppression of p53.

Fig. 4

(A) CA renders p53-dependent resistance of colorectal cancer cells to glucose starvation. HCT116p53+/+ or HCT116p53−/− cells were cultured glucose free media in the presence or absence of 5mM of AA (acetic acid) or CA (crotonic acid) for colony formation assays. (B) The quantification of colonies formed from the experiments in panel A is shown here.