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. Author manuscript; available in PMC: 2021 Jun 17.
Published in final edited form as: ChemMedChem. 2020 Apr 28;15(12):1058–1066. doi: 10.1002/cmdc.202000137

Figure 1.

Figure 1.

Interactions of the alkyl group of the benzamide capping group in compound 21 with the PBD of PLK1 (PDB ID: 3RQ7). The hydrophobic groove exploited by the capping group and the interactions of the phosphothreonine are highlighted.