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. Author manuscript; available in PMC: 2021 Apr 1.
Published in final edited form as: Stem Cells. 2020 Jan 10;38(4):469–476. doi: 10.1002/stem.3140

Figure 2.

Figure 2.

The therapeutic potential of EVs produced by stem cells. The EVs isolated from mesenchymal stem cells (MSCs) have been used to treat various mouse models of disease. These vesicles have been shown to help repair damaged tissues, such that they regain at least a portion of their original function (left side). EVs from stem cells can also be used as a drug delivery system. In this case, the EVs from MSCs are loaded with various types of therapeutic cargo before being administered to the diseased animals. The EV-mediated delivery of therapeutic cargo promotes recovery (right side).