. Author manuscript; available in PMC: 2021 May 1.

Published in final edited form as: Clin Pharmacol Ther. 2019 Dec 31;107(5):1200–1208. doi: 10.1002/cpt.1714

Table 2.

Geometric mean (GM) intracellular TFV-DP and FTC-TP concentrations in the T +PRO and Control IPERGAY treatments and geometric mean ratio (GMR, T/C) and 90% confidence intervals (90% CI).

PBMC Concentration	Tenofovir-DP			Emtricitabine-TP
PBMC Concentration	C	T	GMR (T/C)	C	T	GMR (T/C)
C_24h (fmol/10⁶ cells)	15	20	1.3	1861	2077	1.1
	(13–19)	(17–23)	(1.0–1.6)	(1523–2274)	(1716–2512)	(0.88–1.4)
C_48h (fmol/10⁶ cells)	32	23	0.7	2029	1103	0.54
	(26–19)	(18–28)	(0.52–0.94)	(1569–2624)	(922–1320)	(0.40–0.73)
C_72h (fmol/10⁶ cells)	34	21	0.6	1671	639	0.38
	(29–41)	(16–26)	(0.42–0.86)	(1318–2118)	(488–838)	(0.26–0.56)