TABLE 2.
Comparison of patients with positive exploration at the time of definitive operation to those with a negative exploration at the time of attempted/definitive resection
| Characteristic | Negative exploration (n = 397) | Positive exploration (n = 54) | P-value |
|---|---|---|---|
| Age, median (IQR) | 62.2 (54.1-70.5) | 61.2 (50.6-67.9) | 0.28 |
| Male, no. (%) | 258 (65.0) | 27 (50.0) | 0.03 |
| Race/ethnicity, no. (%) | 0.39* | ||
| White | 250 (63.0) | 29 (53.7) | |
| Black | 26 (6.5) | 3 (5.6) | |
| Asian | 28 (7.1) | 3 (5.6) | |
| Hispanic | 41 (10.3) | 10 (18.5) | |
| Other/unknown | 52 (13.1) | 9 (16.7) | |
| Location, no. (%) | <0.001 | ||
| Gastroesophageal junction or cardia | 194 (48.9) | 17 (31.5) | |
| Antrum/body/fundus | 188 (47.4) | 27 (50.0) | |
| Entire stomach | 15 (3.8) | 10 (18.5) | |
| Grade, no. (%) | 0.001 | ||
| Poorly differentiated | 264 (66.5) | 43 (79.6) | |
| Moderately differentiated | 102 (25.7) | 3 (5.6) | |
| Well differentiated | 2 (0.5) | 0 (0.0) | |
| Unknown | 29 (7.3) | 8 (14.8) | |
| Linitis features present, no. (%) | 26 (6.5) | 15 (27.8) | <0.001* |
| Signet-ring cell morphology present, no. (%) | 178 (44.8) | 35 (64.8) | 0.006 |
| Equivocal cytology at presentation, no. (%) | 9 (2.3) | 2 (3.7) | 0.35* |
| cT category, no. (%) | 0.84* | ||
| T1 | 44 (11.1) | 4 (7.4) | |
| T2 | 7 (1.8) | 1 (1.9) | |
| T3 | 313 (78.8) | 44 (81.5) | |
| T4 | 33 (8.3) | 5 (9.3) | |
| cN category, no. (%) | 0.55 | ||
| N0 | 134 (33.8) | 16 (29.6) | |
| N1+ | 263 (66.2%) | 38 (70.4) | |
| Pre-operative therapy Type | 1.0 | ||
| Chemotherapy and radiation | 344 (86.6) | 47 (87.0) | |
| Chemotherapy only | 53 (13.4) | 7 (13.0) | |
| Surgery delayed by >8 months, no. (%) | 0.66 | ||
| Yes | 85 (21.4) | 13 (24.1) | |
| No | 312 (78.6) | 41 (75.9) |
IQR, interquartile range.
*
Fisher exact test.