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. 2020 Nov 30;15(11):e0242925. doi: 10.1371/journal.pone.0242925

Table 4. Inflammatory markers at preoperative baseline, 8 and 24 hours after surgery.

Variables LA group SA group GA group p-value
(n = 18) (n = 18) (n = 18)
IL-10 level (pg/ml)
 Preoperative baseline 0 (0–4.2) 0 (0–17.5) 0 (0–3.3) 0.545
 8 hours after surgery 4.7 (0–7.2) 5.1 (0–19.6) 3.7 (0–10.5) 0.911
 24 hours after surgery 5.4 (0–13.8) 5.7 (0–19.2) 5.2 (0–10.9) 0.628
IL-6 level (pg/ml)
 Preoperative baseline 0.9 (0–38.2) 2.3 (0–121.1) 0 (0–8.3) 0.318
 8 hours after surgery 30.4 (6.8–78.3) 31.6 (10.4–169.8) 29.8 (9.4–102.3) 0.972
 24 hours after surgery 16.6 (2.3–126.8) 16.1 (2.5–149.3) 15.6 (2.6–71.4) 0.879
IL-1β level (pg/ml)
 Preoperative baseline 0 0 0
 8 hours after surgery 0.5 (0.5–2.6) 0.5 (0.5–3.1) 0.5 (0.5–4.0) 0.761
 24 hours after surgery 0.5 (0.5–3.1) 0.5 (0.5–2.9) 0.5 (0.5–4.2) 0.493

Data presented as median (min–max).

Abbreviations: LA, local anesthesia; SA, spinal anesthesia; GA, general anesthesia.

p-value for Kruskal-Wallis test.