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. 2020 Nov 30;15(11):e0242865. doi: 10.1371/journal.pone.0242865

Table 4. Generalized linear effects models of physical and mental health comorbidity in patients with chronic pain.

Disease Unadjusted (U) U +Socio Demographic variable (SD) U+SD+ Total number of Physical illness (PT) U+SD+ Total number of Mental illness (MT) U+SD+PT+MT U+SD+PT+MT+ Interaction (I)
  OR (95%CI) p value OR (95%CI) p value OR (95%CI) p value OR (95%CI) p value OR (95%CI) p value OR (95%CI) p value
Hypertension 2.61 (2.279,2.984) <0.001 1.66 (1.424,1.935) <0.001 1.59 (1.364,1.861) <0.001 1.64 (1.402,1.913) <0.001 1.58 (1.35,1.85) <0.001 1.58 (1.353,1.854) <0.001
Diabetes Mellitus 2.21 (1.921,2.544) <0.001 1.46 (1.245,1.713) <0.001 1.39 (1.182,1.636) <0.001 1.47 (1.249,1.726) <0.001 1.41 (1.196,1.661) <0.001 1.41 (1.198,1.663) <0.001
Epilepsy 1.29 (0.657,2.517) 0.463 1.09 (0.509,2.337) 0.823 1.21 (0.564,2.603) 0.624 0.96 (0.447,2.075) 0.923 1.08 (0.499,2.32) 0.852 1.01 (0.466,2.2) 0.976
Tuberculosis 2.8 (1.52,5.154) 0.001 3.29 (1.649,6.584) 0.001 3.49 (1.737,6.997) <0.001 2.87 (1.431,5.748) 0.003 3.02 (1.506,6.041) 0.002 2.81 (1.393,5.654) 0.004
Dermatological conditions 1.14 (0.809,1.593) 0.462 1.15 (0.785,1.678) 0.476 1.31 (0.896,1.928) 0.162 1.15 (0.781,1.683) 0.486 1.3 (0.88,1.913) 0.188 1.3 (0.879,1.916) 0.19
Arthritis 7.99 (5.691,11.222) <0.001 5.86 (4.029,8.512) <0.001 6.99 (4.781,10.22) <0.001 5.65 (3.857,8.266) <0.001 6.69 (4.541,9.842) <0.001 6.62 (4.491,9.76) <0.001
Asthma 2 (1.427,2.79) <0.001 1.47 (1.008,2.131) 0.045 1.73 (1.181,2.523) 0.005 1.34 (0.915,1.958) 0.133 1.57 (1.065,2.315) 0.023 1.58 (1.071,2.321) 0.021
Others 1.55 (1.311,1.822) <0.001 1.53 (1.277,1.83) <0.001 1.75 (1.461,2.107) <0.001 1.48 (1.236,1.78) <0.001 1.7 (1.412,2.047) <0.001 1.69 (1.401,2.03) <0.001
Alcohol hazardous use 1.06 (0.706,1.58) 0.791 1.3 (0.836,2.018) 0.245 1.31 (0.84,2.041) 0.234 0.97 (0.614,1.526) 0.889 1 (0.634,1.58) 0.998 0.98 (0.621,1.546) 0.93
Tobacco Dependence 1.43 (1.09,1.875) 0.01 2.04 (1.499,2.774) <0.001 2.2 (1.615,3.005) <0.001 1.74 (1.27,2.387) 0.001 1.9 (1.38,2.605) <0.001 1.85 (1.343,2.542) <0.001
Depression 5.12 (3.997,6.558) <0.001 4.07 (3.112,5.324) <0.001 3.62 (2.76,4.748) <0.001 3.53 (2.684,4.64) <0.001 3.12 (2.367,4.115) <0.001 3.12 (2.37,4.118) <0.001
Anxiety 4.24 (3.144,5.726) <0.001 3.28 (2.346,4.573) <0.001 3.08 (2.198,4.31) <0.001 2.41 (1.705,3.396) <0.001 2.28 (1.613,3.23) <0.001 2.32 (1.64,3.274) <0.001