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. 2020 Nov 30;15(11):e0242827. doi: 10.1371/journal.pone.0242827

Fig 5. Histological lung injury score.

Fig 5

Rats were subjected to fast brain death (BD) induction (intracranial pressure (ICP) increase over 1 min) versus slow BD induction (ICP increase over 30 min). Lungs were procured after 0.5–4 hours of donor stabilization and histological lung injury scores were assessed. All values are presented as mean. Asterisks denote significant differences between the two BD models per time point: * p<0.05. ‘#’-symbols indicate significant differences compared to controls. X-axis 0.5–4 hours–brain-dead group with period of ventilation and hemodynamic stabilization time; Control–immediately sacrificed without intervention; FM—fast BD induction model, expansion of the Fogarty catheter over 1 min; SM—slow BD induction model, expansion of the Fogarty catheter over 30 min.