Table 2. Toxicities Reported with Treatment.
R-CHOP, Rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone.
CTCAE, Common Terminology Criteria for Adverse Events.
DA-REPOCH, Dose-adjusted rituximab, etoposide, prednisone, vincristine, cyclophosphamide, and doxorubicin.
All toxicities reported in our patient population are listed. Toxicities are graded according to CTCAE version 5.
| R-CHOP | CTCAE v5 any grade | CTCAE v5 Grade 3 or higher |
| No. (% of total population) | ||
| Any | 10 (83%) | 6 (50%) |
| Fatigue | 6 (50%) | 2 (17%) |
| Peripheral motor neuropathy | 3 (25%) | 0 (0%) |
| Heart failure | 2 (17%) | 2 (17%) |
| Febrile neutropenia | 3 (25%) | 3 (25%) |
| Lung infection | 1 (8%) | 1 (8%) |
| Rash | 2 (17%) | 0 (0%) |
| Thromboembolic event | 1 (8%) | 1 (8%) |
| Sepsis | 1 (8%) | 1 (8%) |
| Nausea and vomiting | 1 (8%) | 1 (8%) |
| Death | 1 (8%) | 1 (8%) |
| DA-REPOCH | ||
| Any | 7 (78%) | 3 (33%) |
| Fatigue | 4 (44%) | 0 (0%) |
| Peripheral motor neuropathy | 1 (11%) | 0 (0%) |
| Generalized muscle weakness | 1 (11%) | 1 (11%) |
| Mucositis | 1 (11%) | 1 (11%) |
| Nausea and vomiting | 1 (11%) | 1 (11%) |
| Death | 0 (0%) | 0 (0%) |