Table 1.
Parameters of cardiac and renal functions of animals not exposed and exposed to cigarette smoke.
| Control | Smoking | p value | |
|---|---|---|---|
| Hemodynamic | |||
| SBP (mmHg) | 126 ± 2 | 129 ± 2 | p > 0.05 |
| DBP (mmHg) | 84 ± 2 | 82 ± 3 | p > 0.05 |
| MBP (mmHg) | 98 ± 1 | 98 ± 2 | p > 0.05 |
| Myocardial function | |||
| DT (g/mm2/mg) | 1.11 ± 0.57 | 0.95 ± 0.38 | p > 0.05 |
| +dT/dtmax (g/mm2/mg/s) | 10.13 ± 3.57 | 8.63 ± 2.62 | p > 0.05 |
| −dT/dtmax (g/mm2/mg/s) | −8.18 ± 5.88 | −5.43 ± 1.82 | p > 0.05 |
| RT (g/mm2/mg) | 0.22 ± 0.17 | 0.19 ± 0.06 | p > 0.05 |
| Renal function | |||
| SCr (mg/dL) | 0.48 ± 0.05 | 0.47 ± 0.08 | p > 0.05 |
| CrCl (mL/min) | 1.14 ± 0.02 | 1.13 ± 0.05 | p > 0.05 |
| Uprot (mg/24 h) | 16.27 ± 1.60 | 20.15 ± 1.53 | p > 0.05 |
| Uprot/CrCl (mg/mL) | 14.78 ± 1.40 | 18.56 ± 1.20 | p > 0.05 |
Values are the mean ± SEM. Systolic (SBP), diastolic (DBP), and mean blood pressures (MBP) measured in hemodynamic study; developed (DT) and resting tensions (RT) and maximum rate of tension rise (+dT/dtmax) and decline (-dT/dtmax) of isolated cardiac muscles; serum creatinine (SCr), creatinine clearance (ClCr), 24 h urinary excretion (Uprot), and urine protein/creatinine clearance ratio (Uprot/CrCl).