Table 1.
Baseline demographic and clinical characteristics of MTC patients who underwent total thyroidectomy and neck lymph nodes dissection.
| Variables | Training cohort (%) (n = 867) | Test cohort (%) (n = 370) |
|---|---|---|
| Age (y) | ||
| <48 | 299 (34.5) | 137 (37.0) |
| 48–71 | 468 (54.0) | 184 (49.7) |
| >71 | 100 (11.5) | 49 (13.3) |
|
| ||
| Race | ||
| Black | 67 (7.7) | 28 (7.6) |
| White | 740 (85.4) | 319 (86.2) |
| Others | 60 (6.9) | 23 (6.2) |
|
| ||
| Sex | ||
| Male | 388 (44.8) | 141 (38.1) |
| Female | 479 (55.2) | 229 (61.9) |
|
| ||
| Number of nodules | ||
| Solitary | 589 (67.9) | 260 (70.3) |
| Multiple | 278 (32.1) | 110 (29.7) |
|
| ||
| Tumor size(mm) | ||
| <20 | 381 (43.9) | 162 (43.8) |
| 20–40 | 318 (36.7) | 151 (40.8) |
| >40 | 168 (19.4) | 57 (15.4) |
|
| ||
| T | ||
| T1a | 168 (19.4) | 83 (22.4) |
| T1b | 175 (20.2) | 77 (20.8) |
| T2 | 204 (23.5) | 92 (24.9) |
| T3a | 118 (13.6) | 48 (13.0) |
| T3b | 125 (14.4) | 42 (11.4) |
| T4a | 52 (6.0) | 17 (4.6) |
| T4b | 25 (2.9) | 11 (3.0) |
|
| ||
| N | ||
| N0 | 391 (45.1) | 200 (54.1) |
| N1a | 169 (19.5) | 48 (13.0) |
| N1b | 307 (35.4) | 122 (33.0) |
|
| ||
| M | ||
| M0 | 810 (93.4) | 354 (95.7) |
| M1 | 57 (6.6) | 16 (4.3) |
|
| ||
| Number of removal LNs | ||
| 1–3 | 158 (18.2) | 70 (18.9) |
| ≥4 | 709 (81.8) | 300 (81.1) |
|
| ||
| Total LNs | ||
| 0–11 | 367 (42.3) | 178 (48.1) |
| 12–32 | 253 (29.2) | 89 (24.1) |
| 33–90 | 247 (28.5) | 103 (27.8) |
|
| ||
| PLNs | ||
| 0 | 393 (45.3) | 200 (54.1) |
| 1–16 | 378 (43.6) | 130 (35.1) |
| 17–73 | 96 (11.1) | 40 (10.8) |
|
| ||
| LNR | ||
| <19.0% | 514 (59.3) | 250 (67.6) |
| 19.0%–49.0% | 191 (22.0) | 60 (16.2) |
| >49.0% | 162 (18.7) | 60 (16.2) |
Number of removal LNs, number of removal lymph nodes; total LNs, the number of regional lymph nodes by pathological findings; pLNs, positive lymph nodes; LNR, lymph node ratio.