Year of publication |
Age/gender |
Prior Neurosurgical interventions |
Comorbid illnesses |
Therapy (Duration ) |
Outcome |
Patrick et al 1975 [5] |
70 years/M |
None |
Emphysema |
Sulphamidine and chloramphenicol (12 days) |
Cured |
Denis et al, 1977 [6] |
13 months/F |
None |
None |
Chloramphenicol and sulfadoxime/duration* |
Cured |
Denis et al, 1977 [6] |
8 months/M |
None |
None |
Ampicillin and colistin* |
Died |
Trump et al, 1982 [7] |
52 years/F |
Ommaya reservoir |
Metastatic malignancy |
Chloramphenicol and gentamicin* |
Cured |
Dewi et al, 1984 [8] |
Preterm infant/M |
Yes |
IVH |
none |
Died |
Muder et al, 1987 [9] |
65 years/M |
EVD |
IVH |
TMP-SXM* |
Cured |
Girijaratnakum-ari et al, 1993 [10] |
28 years/F |
craniotomy |
CP angle tumor |
I/V ciprofloxacin (3 weeks) |
Cured |
Nguyen et al,1994 [11] |
64 years/M |
VPS |
Meningioma |
I/V TMP-SX with intrathecal gentamicin* |
Cured |
Papadakis et al, 1997 [12] |
36 years/F |
Ommaya reservoir |
Melanoma |
TMP-SXM* |
Cured |
Papadakis et al, 1997 [12] |
41 years/M |
Ommaya reservoir |
Autologous SCT |
TMP-SXM* |
Died |
Spencer et al, 2001 [13] |
31 years/F |
No |
None |
TMP-SXM (14 days) |
Cured |
Caylan et al,2002 [14] |
52 years/M |
VPS |
SAH |
TMP-SXM DS (3 weeks) |
Cured |
Platsouka et al, 2002 [15] |
42 years/M |
Yes |
Malignancy |
TMP-SXM with ceftazidime * |
Cured |
Lo et al, 2002 [16] |
Preterm infant/F |
No |
None |
Ciprofloxacin (4 weeks) |
Cured |
Libanore et al, 2004 [17] |
49 years/M |
No |
None |
Amikacin with ceftazidime (14 days ) |
Cured |
Reddy et al , 2006 [18] |
48 years/M |
craniotomy |
Pituitary tumor |
TMP-SXM (12 days )followed by moxifloxacin (21 days) |
Cured |
Yemisen et al , 2008 [2] |
30 years/M |
Craniotomy |
Subdural hematoma |
Ciprofloxacin and TMP-SXM (14 days) |
Cured |
Rojas et al , 2009 [19] |
Preterm/M |
Yes |
Nil |
Ciprofloxacin and TMP-SXM (21 days) |
Cured |
Huang et al ,2013 [4] |
48 years/M |
Craniotomy and EVD |
Nil |
IV TMP-SXM + IV ciprofloxacin (23 days) |
Cured |
Huang et al ,2013 [4]. |
61 years/M |
craniotomy and EVD |
Nil |
IV ceftazidime (63 days ) → IV ciprofloxacin (35 days ) |
Cured |
Huang et al , 2013 [4]. |
43 years/F |
craniotomy and EVD |
Intracranial artery aneurysm |
Oral TMP-SXM (33) + IV levofloxacin (11)→ IV ciprofloxacin (22) |
Cured |
Huang et al,2013 [4] |
48 years/F |
craniotomy and EVD |
intracranial artery aneurysm |
IV TMP - SXM + IV moxifloxacin (42 days) |
Cured |
Huang et al, 2013 [4] |
62 years/F |
craniotomy and EVD |
DM |
IV SMZ–TMP (61)+ IV moxifloxacin (42) (28) |
Died |
Huang et al,2013 [4] |
45 years/M |
craniotomy and VP shunt |
Pituitary tumor |
IV moxifloxacin → IV moxifloxacin+ oral TMP-SXM (14) |
Died |
Wang et al, 2013 [3] |
73 years/M |
Yes, EVD |
Nil |
Ceftazidime (21 days) |
Cured |
Wang et al, 2013 [3] |
61 years/M |
Neuro endoscopy |
Nil |
Ceftazidime (21 days) |
Cured |
Correia et al, 2014 [20] |
4 years/M |
EVD |
Nil |
TMP-SMX + ceftazidime + levofloxacin 21 days |
Cured |
Ibrahim et al,2018 [1] |
13 days old/M |
No |
Nil |
TMP-SMX and Ciprofloxacin (21 days) |
Cured |
Present case |
35 years/M |
Yes /VP shunt |
Nil |
TMP-SMX and ceftazidime (21 days) |
Cured |
Present case |
60 years/F |
Yes/EVD |
HTN |
TMP-SMX and colistin – (21 days) |
Cured |