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. 2020 Oct 28;12(10):e11221. doi: 10.7759/cureus.11221

Table 3. . Cases with S. maltophilia meningitis .

 F: female, M: male, TMP-SXM: Trimethoprim- sulfamethoxazole, IVH: intraventricular haemorrhage, SCT: stem cell transplant, EVD: external ventricular drain, VPS: ventriculo peritoneal shunt,  HTN: hypertension, SAH:  subarachnoid haemorrhage   *duration not known

 Year of publication Age/gender Prior Neurosurgical interventions Comorbid illnesses Therapy (Duration ) Outcome
Patrick et al  1975 [5] 70 years/M   None Emphysema Sulphamidine and chloramphenicol (12 days) Cured
Denis et al, 1977 [6] 13 months/F None None Chloramphenicol and sulfadoxime/duration* Cured
Denis et al,  1977 [6] 8 months/M None None Ampicillin and colistin* Died
Trump et al, 1982 [7] 52 years/F Ommaya reservoir Metastatic malignancy Chloramphenicol and gentamicin* Cured
Dewi et al, 1984 [8] Preterm infant/M Yes IVH none Died
Muder et al, 1987 [9] 65 years/M EVD IVH TMP-SXM* Cured
Girijaratnakum-ari et al,  1993 [10] 28 years/F craniotomy   CP angle tumor I/V ciprofloxacin (3 weeks) Cured
Nguyen et al,1994 [11] 64 years/M VPS Meningioma I/V TMP-SX with intrathecal gentamicin* Cured
Papadakis et al, 1997 [12] 36 years/F   Ommaya reservoir Melanoma TMP-SXM* Cured
Papadakis et al, 1997 [12] 41 years/M Ommaya reservoir Autologous SCT TMP-SXM* Died
Spencer et al, 2001 [13] 31 years/F  No None TMP-SXM (14 days) Cured
Caylan et al,2002 [14] 52 years/M  VPS SAH TMP-SXM DS (3 weeks) Cured
Platsouka et al, 2002  [15] 42 years/M Yes Malignancy TMP-SXM with ceftazidime * Cured
Lo et al, 2002 [16] Preterm infant/F No None Ciprofloxacin (4 weeks) Cured
Libanore et al, 2004 [17] 49 years/M No None Amikacin with ceftazidime (14 days ) Cured
Reddy et al , 2006 [18] 48 years/M   craniotomy Pituitary tumor TMP-SXM  (12 days )followed by moxifloxacin (21 days) Cured
Yemisen et al ,  2008 [2] 30 years/M Craniotomy Subdural hematoma Ciprofloxacin and TMP-SXM (14 days) Cured
Rojas et al , 2009 [19] Preterm/M Yes Nil Ciprofloxacin and TMP-SXM  (21 days) Cured
Huang  et al ,2013 [4] 48 years/M Craniotomy and EVD   Nil IV TMP-SXM  + IV ciprofloxacin (23 days) Cured
Huang  et al ,2013 [4]. 61 years/M craniotomy and EVD Nil IV ceftazidime (63 days ) → IV ciprofloxacin (35 days ) Cured
Huang  et al , 2013 [4]. 43 years/F   craniotomy and EVD Intracranial artery aneurysm Oral TMP-SXM (33) + IV levofloxacin (11)→ IV ciprofloxacin (22)   Cured
Huang  et al,2013 [4] 48 years/F craniotomy and EVD intracranial artery  aneurysm IV TMP - SXM + IV moxifloxacin  (42 days) Cured
Huang  et al, 2013 [4] 62 years/F   craniotomy and EVD DM IV SMZ–TMP (61)+ IV moxifloxacin (42) (28) Died
Huang  et al,2013 [4] 45 years/M   craniotomy and VP shunt Pituitary tumor IV moxifloxacin → IV moxifloxacin+ oral TMP-SXM (14)   Died
Wang et al, 2013 [3] 73 years/M Yes, EVD   Nil Ceftazidime  (21 days) Cured
Wang et al, 2013 [3] 61 years/M Neuro endoscopy Nil Ceftazidime (21 days) Cured
Correia et al, 2014  [20] 4 years/M EVD Nil TMP-SMX  +  ceftazidime  + levofloxacin  21 days Cured
Ibrahim et al,2018 [1] 13 days old/M No Nil TMP-SMX and Ciprofloxacin (21 days) Cured
Present case 35 years/M Yes /VP shunt Nil TMP-SMX and ceftazidime (21 days) Cured
Present case 60 years/F Yes/EVD HTN TMP-SMX and colistin – (21 days) Cured