Table 2.
Diagnostic performance of kinetic parameters of two tracer kinetic models in distinguishing IDH-mutant from IDH-wildtype gliomas.
| Model | Parameters | AUC | Cutoff value | Sensitivity (%) | Specificity (%) | Accuracy (%) |
|---|---|---|---|---|---|---|
| Tofts | K trans (min−1) | 0.69 | 0.02 | 50.0 | 96.8 | 72.7 |
| Ve (mL/100 mL) | 0.79 | 2.81 | 66.7 | 87.1 | 78.2 | |
| Kep (min−1) | 0.55 | 0.40 | 37.5 | 67.7 | 67.3 | |
| DP | F (mL/min/100 mL) | 0.69 | 6.08 | 37.5 | 100.0 | 63.6 |
| PS (mL/min/100 mL) | 0.81 | 2.30 | 83.3 | 77.4 | 80.0 | |
| E (%) | 0.80 | 5.98 | 70.8 | 90.3 | 81.8 | |
| Ve (mL/100 mL) | 0.75 | 2.03 | 62.5 | 90.3 | 78.2 | |
| Vp (mL/100 mL) | 0.92 | 0.74 | 87.5 | 80.7 | 83.6 |