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. 2020 Nov 21;2020:8816737. doi: 10.1155/2020/8816737

(b).

Intervention (mean) Recurrence Refractory AEs Use of concurrent (anti-TNF)
Fixed cell dose 7 months without recurrence Yes Yes
 First: 2 × 107 MSCs
 Second: 4 × 107 MSCs
Fixed cell dose Two completely healed patients were followed up for 4 years without recurrence Yes Yes
 First: 2 × 107 MSCs
 Second: 4 × 107 MSCs
Fixed cell dose Unknown Yes No
 First: 2 × 107 MSCs
 Second: 4 × 107 MSCs
Fixed cell dose 24 w without recurrence Yes Yes
 A: 1 × 107 MSCs
 B: 3 × 107 MSCs
 C: 9 × 107 MSCs
Fixed cell dose Being follow-up Yes 68/103 in MSCs vs. 66/102 in placebo at 24 w Yes
 12 × 107 MSCs
Fixed cell dose Being follow-up Yes 79/103 in MSCs vs. 74/102 in placebo at 52 w Yes
 12 × 107 MSCs
Fixed cell dose Recurrence of the fistula was observed at 2-year follow-up in eight previously cured patients Unknown 7/23 MSCs+fibrin glue vs. 9/21 fibrin glue No
 First: 10 × 107 MSCs
 Second: 10 × 107 MSCs