Table 3.

Univariate and multivariate analysis of variables affecting overall survival (pre-PSM)

Variable	Univariate			Multivariate
	P value	HR	95% CI	P value	HR	95% CI
Sex	0.801	0.830	0.195–3.533
Maximum tumor diameter (<3/3–5/>5 cm)	0.002a	3.670	1.630–8.264	0.194	1.837	0.734–4.597
Number of tumors (single/multiple)	0.052	2.236	0.992–5.043
MVI	0.004a	3.837	1.521–9.680	0.363	1.756	0.522–5.912
Cirrhosis	0.058	4.073	0.956–17.356
IHC (HBsAg, −/+)	0.017a	2.574	1.194–5.922	0.021a	2.841	1.169–6.905
C-reactive protein	0.002a	4.125	1.707–9.968	0.283	1.712	0.642–4.562
HBV DNA level, 10 000 IU/ml	0.186	1.812	0.752–4.371
Ascites	0.028	2.524	1.102–5.778	0.009a	3.346	1.360–8.233
AFP (ng/ml, ≤400/>400)	0.009a	2.967	1.317–6.686	0.006a	3.331	1.199–7.525

AFP, alpha-fetoprotein; CI, confidence interval; HBV, hepatitis B virus; HR, hazard ratio; MVI, microvascular invasion.

^aStatistically significant.