Table 2.

Demographic and socioeconomic factors associated with SARS-CoV-2 seroprevalence in HCWs and support staff. Both unadjusted and inverse probability weight-adjusted regression data are presented. For factors with multiple categories, the 15 most populous are presented and the remaining collated into “other”, which forms the reference group. Abbreviations: IPW – inverse probability weight; OR – odds ratio; CI – confidence interval; BAME – Black, Asian and Minority Ethnic.

	Unadjusted model			IPW-adjusted model
Characteristic	OR^a	95% CI^a	p-value	OR^a	95% CI^a	p-value
Ethnicity
White	—	—		—	—
BAME	1.76	1.40, 2.21	<0.001	1.99	1.69, 2.34	<0.001
Undisclosed	1.33	0.76, 2.18	0.3	1.16	0.81, 1.61	0.4
Gender
Female	—	—		—	—
Male	1.01	0.80, 1.28	>0.9	0.96	0.81, 1.14	0.7
Age
31–40	—	—		—	—
<=20 years	1.06	0.53, 1.98	0.9	1.47	0.96, 2.20	0.071
>=71 years	0.86	0.05, 4.47	0.9	0.74	0.17, 2.08	0.6
21–30	1.5	1.16, 1.95	0.002	1.64	1.36, 1.99	<0.001
41–50	1.32	1.01, 1.74	0.045	1.36	1.11, 1.67	0.003
51–60	1.23	0.92, 1.64	0.2	1.45	1.17, 1.80	<0.001
61–70	1.31	0.85, 1.98	0.2	1.28	0.94, 1.73	0.1
Neighbourhood deprivation	1.01	0.97, 1.04	0.7	0.99	0.96, 1.02	0.5
specialty
Other	—	—		—	—
Cluster 1 – Neurosurgery, spines and pain	0.89	0.50, 1.49	0.7	0.84	0.51, 1.32	0.5
Cluster 2 – Trauma and orthopaedics	1.46	0.91, 2.27	0.11	1.44	0.96, 2.10	0.067
Cluster 3	0.96	0.56, 1.56	0.9	0.94	0.61, 1.41	0.8
Critical care services	0.31	0.11, 0.70	0.013	0.29	0.13, 0.57	0.001
Domestics	0.94	0.53, 1.65	0.8	0.99	0.66, 1.48	>0.9
General surgery services	0.62	0.31, 1.12	0.14	0.62	0.35, 1.03	0.081
Imaging	0.8	0.46, 1.31	0.4	0.86	0.55, 1.28	0.5
Maternity services	0.67	0.31, 1.31	0.3	0.75	0.41, 1.29	0.3
Medicine Cluster 1	1.75	1.24, 2.43	0.001	1.72	1.30, 2.25	<0.001
Medicine Cluster 2	3.43	2.51, 4.67	<0.001	3.35	2.61, 4.30	<0.001
Medicine Cluster 4	3.01	2.05, 4.37	<0.001	2.84	2.07, 3.85	<0.001
Other bank services	1.42	0.95, 2.07	0.077	1.17	0.93, 1.46	0.2
Pathology services	0.51	0.22, 1.03	0.083	0.53	0.28, 0.90	0.028
Theatre services	0.3	0.14, 0.57	<0.001	0.29	0.15, 0.49	<0.001
Therapies services	1.21	0.72, 1.96	0.4	1.29	0.83, 1.93	0.2
Role
Other	—	—		—	—
Assistant	1.56	0.97, 2.44	0.059	1.39	0.99, 1.93	0.051
Clerical worker	0.74	0.48, 1.12	0.2	0.81	0.59, 1.11	0.2
Consultant	0.86	0.52, 1.37	0.5	0.84	0.57, 1.23	0.4
Foundation year 2	1.46	0.71, 2.80	0.3	2.11	1.40, 3.13	<0.001
Health care support worker	2.28	1.27, 4.07	0.005	2.79	2.05, 3.82	<0.001
Healthcare assistant	1.57	1.12, 2.19	0.008	1.52	1.17, 1.98	0.002
Healthcare science assistant	0.41	0.12, 1.06	0.1	0.35	0.14, 0.73	0.01
Healthcare science practitioner	0.09	0.01, 0.45	0.022	0.07	0.01, 0.31	0.004
Housekeeper	1.67	0.97, 2.77	0.054	1.52	1.01, 2.26	0.041
Manager	0.89	0.43, 1.69	0.7	0.86	0.48, 1.43	0.6
Midwife	0.76	0.28, 1.94	0.6	0.59	0.27, 1.21	0.2
Officer	0.85	0.51, 1.36	0.5	0.84	0.56, 1.22	0.4
Porter	2.11	1.04, 4.00	0.029	1.57	1.01, 2.40	0.041
Specialty registrar	0.75	0.43, 1.25	0.3	0.62	0.41, 0.91	0.019
Staff Nurse	1.24	0.94, 1.64	0.14	1.35	1.08, 1.69	0.008

OR = Odds Ratio, CI = Confidence Interval.