2.

RUNX1基因突变与预后核型及完全缓解的相关性

Correlation of RUNX1 mutations with prognostic karyotype and complete remission inAML patients

Variable	Total	RUNX1mutated	RUNX1wildtype	P
Age (year)				0.005
≥60	69	14 (20.28)	55 (79.71)
< 60	89	5 (5.62)	84 (94.38)
CR rate (140 analysis)	71/140 (50.71)	3/19 (15.79)	68/121 (56.20)	0.001
Karyotype (152 analysis)				0.198
Normal	75	12 (16.00)	63 (84.00)
Abnormal	77	7 (9.09)	70 (90.91)
Cytogenetic risk group (152 analysis)				0.069
Favorable	30	0 (0.00)	30 (22.56)
Intermediate	72	11 (57.89)	61 (45.86)
Adverse	50	8 (42.11)	42 (31.58)