Table 4.

Performance of PHQ-9 cut-off scores for detecting major depression.

Cut-Off score	Sensitivity	Specificity	Youden J index	PPV	NPV	CUI+	CUI-	LR+	LR–
≥ 6	0.95	0.76	0.71	0.13	0.99	0.12	0.75	3.95	0.06
≥ 7	0.81	0.81	0.62	0.14	0.99	0.11	0.80	4.25	0.24
≥ 8	0.71	0.85	0.56	0.16	0.99	0.11	0.84	4.90	0.33
≥ 9	0.67	0.87	0.54	0.17	0.99	0.11	0.86	5.3	0.38
≥ 10	0.57	0.90	0.47	0.17	0.98	0.10	0.88	5.48	0.48
≥ 11	0.52	0.93	0.45	0.22	0.98	0.11	0.91	7.47	0.51
≥ 12	0.52	0.94	0.46	0.26	0.98	0.14	0.92	9.10	0.51
≥ 13	0.43	0.95	0.38	0.26	0.98	0.11	0.93	9.16	0.6
≥ 14	0.43	0.97	0.40	0.32	0.98	0.14	0.95	12.54	0.59
≥ 15	0.38	0.97	0.35	0.32	0.98	0.12	0.95	12.46	0.64

PPV, Positive predictive value; NPV, Negative predictive value; CUI+, Clinical utility index positive; CUI–, Clinical utility index negative; LR+, Likelihood ratio positive; LR–, Likelihood ratio negative.