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. Author manuscript; available in PMC: 2022 Apr 1.
Published in final edited form as: J Clin Gastroenterol. 2021 Apr 1;55(4):350–354. doi: 10.1097/MCG.0000000000001365

Table 3:

Adjusted odds of an inflammatory bowel disease patient having meningitis in the Quintiles IMS Legacy PharMetrics Adjudicated Claims Database between January 2001 and June 2016 in a nested case-control study

aOR 95% CI
CCI# > 0 2.21 (1.76 – 2.77)
5-ASA* 0.40 (0.26 – 0.62)
Thiopurine 1.56 (0.88 – 2.76)
Anti-TNF# 0.79 (0.32 – 1.92)
Systemic Corticosteroids^ 1.54 (0.99 – 2.40)
Region: East Referent Referent
Region: Midwest 0.68 (0.51 – 0.90)
Region: South 0.87 (0.67 – 1.12)
Region: West 0.64 (0.45 – 0.91)

Odds Ratios (ORs) are adjusted for type of IBD, current age, sex, comorbidity index, region and IBD medications

#

Deyo modification of the Charlson Comorbidity Index

*

5-Aminosalicylates: oral formulations only

#

TNF: Anti-Tumor Necrosis Factor-α

^

Defined as ≥ 2 week course of any oral systemic formulation