Table 3:
Adjusted odds of an inflammatory bowel disease patient having meningitis in the Quintiles IMS Legacy PharMetrics Adjudicated Claims Database between January 2001 and June 2016 in a nested case-control study
| aOR | 95% CI | |
|---|---|---|
| CCI# > 0 | 2.21 | (1.76 – 2.77) |
| 5-ASA* | 0.40 | (0.26 – 0.62) |
| Thiopurine | 1.56 | (0.88 – 2.76) |
| Anti-TNF# | 0.79 | (0.32 – 1.92) |
| Systemic Corticosteroids^ | 1.54 | (0.99 – 2.40) |
| Region: East | Referent | Referent |
| Region: Midwest | 0.68 | (0.51 – 0.90) |
| Region: South | 0.87 | (0.67 – 1.12) |
| Region: West | 0.64 | (0.45 – 0.91) |
Odds Ratios (ORs) are adjusted for type of IBD, current age, sex, comorbidity index, region and IBD medications
Deyo modification of the Charlson Comorbidity Index
5-Aminosalicylates: oral formulations only
TNF: Anti-Tumor Necrosis Factor-α
Defined as ≥ 2 week course of any oral systemic formulation