Table 4.
Weighted* Odds Ratios (95% Confidence Intervals) of Atrial Fibrillation Burden with Individual Life’s Simple 7 Components: The Atherosclerosis Risk in Communities Study, 1993–2017
| Atrial Fibrillation Burden | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Intermittent vs. none | Continuous vs. none | Continuous vs. intermittent | |||||||
| Model 1 | Model 2 | Model 3 | Model 1 | Model 2 | Model 3 | Model 1 | Model 2 | Model 3 | |
| Physical activity | |||||||||
| Poor | 1.10 (0.62-1.94) | 1.09 (0.61-1.95) | 1.08 (0.60-1.92) | 1.51 (0.99-2.32) | 1.64 (1.06-2.56) | 1.56 (0.98-2.47) | 1.38 (0.69-2.77) | 1.51 (0.74-3.07) | 1.45 (0.70-2.99) |
| Intermediate | 1.85 (1.09-3.15) | 1.83 (1.08-3.12) | 1.84 (1.08-3.13) | 1.09 (0.66-1.82) | 1.12 (0.67-1.86) | 1.08 (0.63-1.82) | 0.59 (0.29-1.21) | 0.61 (0.30-1.25) | 0.59 (0.28-1.22) |
| Ideal | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) |
| Total cholesterol | |||||||||
| Poor | 1.59 (0.89-2.86) | 1.58 (0.88-2.85) | 1.53 (0.85-2.76) | 0.85 (0.47-1.53) | 0.88 (0.49-1.57) | 0.71 (0.39-1.30) | 0.54 (0.24-1.20) | 0.55 (0.25-1.24) | 0.46 (0.20-1.06) |
| Intermediate | 0.93 (0.56-1.55) | 0.92 (0.55-1.54) | 0.89 (0.53-1.49) | 0.99 (0.67-1.49) | 1.01 (0.67-1.51) | 0.89 (0.59-1.36) | 1.07 (0.57-2.02) | 1.09 (0.58-2.06) | 1.00 (0.52-1.92) |
| Ideal | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) |
| Blood pressure | |||||||||
| Poor | 1.22 (0.60-2.47) | 1.20 (0.59-2.44) | 0.98 (0.46-2.07) | 1.22 (0.67-2.23) | 1.29 (0.70-2.36) | 0.56 (0.29-1.09) | 1.00 (0.41-2.48) | 1.08 (0.43-2.67) | 0.57 (0.21-1.52) |
| Intermediate | 1.18 (0.72-1.92) | 1.15 (0.70-1.89) | 1.00 (0.60-1.68) | 1.61 (1.05-2.45) | 1.65 (1.08-2.52) | 1.14 (0.72-1.80) | 1.37 (0.72-2.57) | 1.43 (0.76-2.70) | 1.13 (0.58-2.22) |
| Ideal | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) |
| Body mass index | |||||||||
| Poor | 1.67 (0.96-2.90) | 1.64 (0.94-2.86) | 1.61 (0.92-2.81) | 2.30 (1.37-3.84) | 2.36 (1.41-3.97) | 1.83 (1.08-3.13) | 1.38 (0.66-2.87) | 1.44 (0.69-3.01) | 1.14 (0.54-2.42) |
| Intermediate | 0.60 (0.33-1.10) | 0.60 (0.33-1.10) | 0.59 (0.32-1.07) | 1.03 (0.62-1.73) | 1.04 (0.62-1.73) | 0.93 (0.55-1.57) | 1.71 (0.79-3.72) | 1.74 (0.80-3.78) | 1.59 (0.72-3.49) |
| Ideal | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) |
| Fasting blood glucose | |||||||||
| Poor | 1.12 (0.52-2.39) | 1.19 (0.56-2.56) | 1.13 (0.53-2.44) | 2.26 (1.25-4.11) | 2.28 (1.26-4.16) | 1.70 (0.91-3.19) | 2.02 (0.80-5.15) | 1.91 (0.75-4.90) | 1.50 (0.58-3.93) |
| Intermediate | 0.55 (0.32-0.95) | 0.54 (0.31-0.92) | 0.53 (0.31-0.91) | 1.64 (1.09-2.47) | 1.71 (1.13-2.58) | 1.48 (0.97-2.27) | 2.97 (1.54-5.76) | 3.20 (1.65-6.22) | 2.80 (1.43-5.49) |
| Ideal | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) |
| Smoking status | |||||||||
| Poor | 1.27 (0.73-2.23) | 1.28 (0.73-2.26) | 1.28 (0.73-2.26) | 0.63 (0.35-1.15) | 0.65 (0.36-1.18) | 0.57 (0.30-1.06) | 0.50 (0.22-1.10) | 0.51 (0.23-1.13) | 0.44 (0.19-1.02) |
| Intermediate | 2.19 (0.49-9.77) | 2.23 (0.50-9.99) | 2.27 (0.50-10.3) | 4.55 (1.75-11.8) | 4.60 (1.76-12.1) | 3.86 (1.39-10.7) | 2.09 (0.39-10.9) | 2.07 (0.39-11.0) | 1.70 (0.31-9.45) |
| Ideal | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) |
| Diet | |||||||||
| Poor | 0.42 (0.15-1.20) | 0.46 (0.16-1.33) | 0.49 (0.17-1.43) | 1.80 (0.26-12.4) | 1.74 (0.25-12.0) | 2.21 (0.30-16.0) | 4.31 (0.50-37.2) | 3.76 (0.43-32.7) | 4.47 (0.50-40.4) |
| Intermediate | 0.36 (0.13-1.01) | 0.40 (0.14-1.13) | 0.41 (0.14-1.17) | 1.94 (0.28-13.3) | 1.85 (0.27-12.7) | 2.18 (0.30-15.6) | 5.43 (0.64-46.2) | 4.62 (0.54-39.6) | 5.31 (0.60-47.2) |
| Ideal | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) |
*
Inverse probability weighting was used.
Model 1: adjusted for age, sex, race/center.
Model 2: adjusted for model 1 plus education and drinking status.
Model 3: adjusted for model 2 plus coronary heart disease, stroke, heart failure, beta-blockers, and calcium-channel blockers (measured at Visit 6).