Table 2.
Mixed model analysis to characterize the amplitude of cortico-cortical evoked potentials (CCEPs) elicited by stimulation of different regions.
| Parameters | Estimate | S.E. | df | t | Pr(>∣t∣) | 95% CI | |
|---|---|---|---|---|---|---|---|
| L.L. | U.L. | ||||||
| (Intercept) | +0.0 | 5.3 | 9.8 | 0.001 | 0.999 | −11.8 | 11.8 |
| Deep white matter stimulation | +13.3 | 1.3 | 6343.8 | 10.352 | <0.001 | 10.8 | 15.8 |
| Shallow white matter stimulation |
+10.9 | 1.3 | 7000.6 | 8.560 | <0.001 | 8.4 | 13.4 |
| Gray matter stimulation |
+0.7 | 1.2 | 5241.6 | 0.568 | 0.570 | −1.6 | 2.9 |
| Recording with depth electrodes |
+9.3 | 5.6 | 7.6 | 1.650 | 0.140 | −3.8 | 22.5 |
| Recording in the contralateral contacts |
−21.6 | 1.3 | 8526.2 | −17.155 | <0.001 | −24.0 | −19.1 |
S.E.: Standard error. df: Degree of freedom. Pr: Probability. CI: Confidence interval. L.L.: Lower limit. U.L.: Upper limit. Each increase of a deep white matter contact was associated with an increase of the CCEP amplitude by 13.3 μV. Recording contacts contralateral to the SPES sites were independently associated with a smaller CCEP amplitude by 21.6 μV.