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. Author manuscript; available in PMC: 2020 Dec 1.
Published in final edited form as: IEEE Trans Med Imaging. 2020 Nov 30;39(12):3879–3890. doi: 10.1109/TMI.2020.3006461

Fig. 8.

Fig. 8.

Clinical CT images, 25% and 50% dose simulation from original dose, and KWIA reconstructions. (a) and (b) contains the full dose, low dose simulation, and 4 KWIA reconstruction results. Two ROI were enlarged to emphasize SNR change. And subtraction images (window level and window center were adjusted for visual observation) were made to show the structural change. Visible SNR and CNR reduction can be observed in 50% and 25% dose simulation cases, and KWIA’s ability of SNR recovery can also be visually captured. In ROIs, the SNR changes can be seen more clearly, the performance of noise reduction in ROI 1 and contrast recovery in ROI 2 can be demonstrated with KWIA. No structural difference can be detected from subtraction images.