Table 2 (a): Rates of clinical cardiovascular disease (CVD) diagnoses and risk factors pre-existing chemotherapy, post-chemotherapy and in the first year before and after chemotherapy.
All CVD includes coronary artery disease (CAD), atrial fibrillation, all heart failure (HF), HF with reduced ejection fraction (HFrEF), HF admission, stroke and myocardial infarction (MI). Cardiovascular risk factors includes hypertension, hyperlipidemia and diabetes mellitus. Abbreviations: Chemotx, chemotherapy.
| Total Cohort (N = 6,754 (%)) | Total number of patients | Pre-existing Comorbidity (Any) | Pre-existing Comorbidity (in 1 year prior to chemotx) | Post chemotx Comorbidity (in 1 year post chemotx) | Post chemotx Comorbidity (Any) |
|---|---|---|---|---|---|
| All CVD | 1,929 (29%) | 908 (13%) | 401 (6%) | 425 (6%) | 1,021 (15%) |
| CAD | 848 (13%) | 461 (7%) | 168 (2%) | 157 (2%) | 387 (6%) |
| Atrial fibrillation | 783 (12%) | 318 (5%) | 156 (2%) | 221 (3%) | 465 (7%) |
| A11HF | 678 (10%) | 189 (3%) | 94 (1%) | 204 (3%) | 489 (7%) |
| HFrEF | 462 (7%) | 130 (2%) | 65 (1%) | 140 (2%) | 332 (5%) |
| HF Admission | 87 (1%) | 16 (0.2%) | 7 (0.1%) | 27 (0.4%) | 71 (1%) |
| Stroke | 331 (5%) | 134 (2%) | 41 (1%) | 67 (1%) | 197 (3%) |
| MI | 214 (3%) | 62 (1%) | 35 (1%) | 54 (1%) | 152 (2%) |
| Hypertension | 3,403 (50%) | 1,898 (28%) | 805 (12%) | 821 (12%) | 1,505 (22%) |
| Hyperlipidemia | 2,570 (38%) | 1,555 (23%) | 429 (6%) | 370 (5%) | 1,015 (15%) |
| Diabetes Mellitus | 1,333 (20%) | 698 (10%) | 341 (5%) | 308 (5%) | 635 (9%) |